Bane of our existence

To say that something or someone is "the bane of my existence"
means that the person or thing is a constant irritant
or source of misery.
"Bane of my existence" has lost its edge to a large degree
over the years,
and today is most often applied to something
that may profoundly annoy us but is certainly bearable.
Meet the bane of our existence... 
TAZ